Statements (38)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
benzodiazepine
sedative general anesthetic |
| gptkbp:ATCCode |
N01AF03
|
| gptkbp:brand |
gptkb:Pentothal
|
| gptkbp:CASNumber |
76-75-5
|
| gptkbp:chemicalFormula |
C11H18N2O2S
|
| gptkbp:color |
white to pale yellow powder
|
| gptkbp:contraindication |
porphyria
|
| gptkbp:discoveredBy |
gptkb:Donalee_L._Tabern
gptkb:Ernest_H._Volwiler 1934 |
| gptkbp:eliminationHalfLife |
5-26 hours
|
| https://www.w3.org/2000/01/rdf-schema#label |
thiopental
|
| gptkbp:IUPACName |
5-ethyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
|
| gptkbp:legalStatus |
controlled substance in many countries
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
242.34 g/mol
|
| gptkbp:notable_for |
historically used as 'truth serum'
first intravenous anesthetic used in clinical practice |
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:produces_effect |
rapid loss of consciousness
|
| gptkbp:PubChem_CID |
5459
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
hypotension
respiratory depression cardiac depression |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:synonym |
gptkb:sodium_thiopental
thiopentone |
| gptkbp:UNII |
4HGS4LZ9HC
|
| gptkbp:used_in |
lethal injection protocols
|
| gptkbp:usedFor |
induction of anesthesia
medically induced coma short-term anesthesia treatment of increased intracranial pressure |
| gptkbp:bfsParent |
gptkb:4-aminobutanoic_acid
|
| gptkbp:bfsLayer |
6
|