|
gptkbp:instanceOf
|
gptkb:sedative
gptkb:general_anesthetic
gptkb:benzodiazepine
|
|
gptkbp:ATCCode
|
N01AF03
|
|
gptkbp:brand
|
gptkb:Pentothal
|
|
gptkbp:CASNumber
|
76-75-5
|
|
gptkbp:chemicalFormula
|
C11H18N2O2S
|
|
gptkbp:color
|
white to pale yellow powder
|
|
gptkbp:contraindication
|
gptkb:porphyria
|
|
gptkbp:discoveredBy
|
gptkb:Donalee_L._Tabern
gptkb:Ernest_H._Volwiler
1934
|
|
gptkbp:eliminationHalfLife
|
5-26 hours
|
|
gptkbp:IUPACName
|
5-ethyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
|
|
gptkbp:legalStatus
|
controlled substance in many countries
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
242.34 g/mol
|
|
gptkbp:notable_for
|
historically used as 'truth serum'
first intravenous anesthetic used in clinical practice
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:produces_effect
|
rapid loss of consciousness
|
|
gptkbp:PubChem_CID
|
5459
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
hypotension
respiratory depression
cardiac depression
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:synonym
|
gptkb:sodium_thiopental
thiopentone
|
|
gptkbp:UNII
|
4HGS4LZ9HC
|
|
gptkbp:used_in
|
lethal injection protocols
|
|
gptkbp:usedFor
|
induction of anesthesia
medically induced coma
short-term anesthesia
treatment of increased intracranial pressure
|
|
gptkbp:bfsParent
|
gptkb:4-aminobutanoic_acid
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
thiopental
|