Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
blood disorder |
| gptkbp:affects |
hemoglobin production
|
| gptkbp:causedBy |
mutations in HBB gene
|
| gptkbp:complication |
pulmonary hypertension
gallstones iron overload leg ulcers |
| gptkbp:diagnosedBy |
blood tests
hemoglobin electrophoresis |
| gptkbp:firstDescribed |
mid-20th century
|
| https://www.w3.org/2000/01/rdf-schema#label |
thalassemia intermedia
|
| gptkbp:inheritance |
autosomal recessive
|
| gptkbp:partOf |
thalassemia syndromes
|
| gptkbp:prevalence |
higher in Mediterranean, Middle Eastern, and South Asian populations
|
| gptkbp:symptom |
jaundice
splenomegaly bone deformities delayed growth mild to moderate anemia |
| gptkbp:treatment |
gptkb:splenectomy
blood transfusions folic acid supplementation iron chelation therapy |
| gptkbp:bfsParent |
gptkb:anemia
|
| gptkbp:bfsLayer |
5
|