Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:small_molecule
gptkb:drug |
| gptkbp:approvalYear |
2018
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
R07AX32
|
| gptkbp:brand |
gptkb:Symkevi
gptkb:Symdeko |
| gptkbp:CASNumber |
1386081-44-3
|
| gptkbp:combines |
gptkb:elexacaftor
gptkb:ivacaftor |
| gptkbp:developedBy |
gptkb:Vertex_Pharmaceuticals
|
| gptkbp:hasMolecularFormula |
C26H28F3N3O3
|
| gptkbp:hasSMILES |
CC1=CC(=O)N(C2=CC=CC=C12)C3=CC=C(C=C3)C4=NC(=C(C(=O)N4)C)C(F)(F)F
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
CFTR modulator
|
| gptkbp:pregnancyCategory |
Not assigned (US)
B1 (Australia) |
| gptkbp:PubChem_CID |
gptkb:CHEMBL3989989
71511961 DB14066 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
dizziness headache sinus congestion |
| gptkbp:synonym |
gptkb:VX-661
|
| gptkbp:UNII |
6X9OC3H4PO
|
| gptkbp:usedFor |
cystic fibrosis
|
| gptkbp:bfsParent |
gptkb:Symdeko
gptkb:Trikafta |
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
tezacaftor
|