Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
small molecule |
gptkbp:administeredBy |
gptkb:ivacaftor
gptkb:tezacaftor |
gptkbp:approvedBy |
gptkb:FDA
2019 |
gptkbp:ATCCode |
gptkb:R07AX31
|
gptkbp:CASNumber |
2114140-23-2
|
gptkbp:component |
gptkb:Kaftrio
gptkb:Trikafta |
gptkbp:developedBy |
gptkb:Vertex_Pharmaceuticals
|
gptkbp:hasMolecularFormula |
C26H32F2N2O6
|
https://www.w3.org/2000/01/rdf-schema#label |
elexacaftor
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
CFTR modulator
|
gptkbp:PubChem_CID |
121439297
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
diarrhea
abdominal pain headache rash upper respiratory tract infection |
gptkbp:UNII |
6X8QF8YF2V
|
gptkbp:usedFor |
cystic fibrosis
|
gptkbp:bfsParent |
gptkb:CFTR_gene
gptkb:CFTR_modulators gptkb:Trikafta |
gptkbp:bfsLayer |
6
|