|
gptkbp:instanceOf
|
gptkb:drug
gptkb:immunomodulatory_agent
|
|
gptkbp:approvalYear
|
2012
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
L04AA31
|
|
gptkbp:brand
|
gptkb:Aubagio
|
|
gptkbp:CASNumber
|
163451-81-8
|
|
gptkbp:chemicalClass
|
isoxazole derivative
|
|
gptkbp:contraindication
|
pregnancy
|
|
gptkbp:developedBy
|
gptkb:Sanofi
|
|
gptkbp:eliminationHalfLife
|
18–19 days
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasMolecularFormula
|
C12H9F3N2O2
|
|
gptkbp:hasSMILES
|
CC1=NC(=C(O1)C2=CC=CC=C2C(=O)NC(F)(F)F)N
|
|
gptkbp:KEGGID
|
D08668
|
|
gptkbp:legalStatus
|
prescription only
patented
|
|
gptkbp:mechanismOfAction
|
dihydroorotate dehydrogenase inhibitor
|
|
gptkbp:MeSH_ID
|
C522113
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
270.21 g/mol
|
|
gptkbp:pregnancyCategory
|
gptkb:X_(US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1237035
gptkb:DB08868
208834
|
|
gptkbp:relatedTo
|
gptkb:leflunomide
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
hypertension
hair thinning
liver enzyme elevation
|
|
gptkbp:UNII
|
G7G0Q9N5F5
|
|
gptkbp:usedFor
|
multiple sclerosis
|
|
gptkbp:bfsParent
|
gptkb:Aubagio
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
teriflunomide
|