Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
gptkb:tryptophan_hydroxylase_inhibitor |
| gptkbp:approvalYear |
2017
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
A16AX14
|
| gptkbp:brand |
gptkb:Xermelo
|
| gptkbp:CASNumber |
1033805-25-6
|
| gptkbp:chemicalFormula |
C30H30FN3O4
|
| gptkbp:developer |
gptkb:Lexicon_Pharmaceuticals
|
| gptkbp:eliminationHalfLife |
5 hours
|
| gptkbp:excretion |
urine
feces |
| gptkbp:KEGGID |
D10813
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits serotonin production
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
515.6 g/mol
|
| gptkbp:pregnancyCategory |
Not assigned (consult physician)
|
| gptkbp:PubChem_CID |
25154894
CHEMBL2103887 DB11838 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
gptkb:depression
nausea abdominal pain elevated liver enzymes |
| gptkbp:UNII |
6Z5B6HVF6O
|
| gptkbp:usedFor |
carcinoid syndrome diarrhea
|
| gptkbp:bfsParent |
gptkb:Xermelo
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
telotristat ethyl
|