t(17;19) translocation in leukemia
GPTKB entity
Statements (17)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chromosomal band
|
| gptkbp:age |
adolescents
children |
| gptkbp:associatedWith |
leukemia
|
| gptkbp:chromosomeInvolved |
gptkb:chromosome_19
gptkb:chromosome_17 |
| gptkbp:firstDescribed |
1991
|
| gptkbp:formsFusionGeneWith |
gptkb:TCF3-HLF
|
| gptkbp:frequency |
rare
|
| gptkbp:hasClinicalFeature |
gptkb:hypercalcemia
refractory to therapy |
| https://www.w3.org/2000/01/rdf-schema#label |
t(17;19) translocation in leukemia
|
| gptkbp:mechanismOfAction |
fusion of TCF3 gene on 19p13 with HLF gene on 17q22
|
| gptkbp:prognosis |
poor
|
| gptkbp:bfsParent |
gptkb:HLF_protein
gptkb:Hepatic_Leukemia_Factor |
| gptkbp:bfsLayer |
7
|