somatic mutation theory of aging

GPTKB entity

Statements (19)
Predicate Object
gptkbp:instanceOf scientific theory
gptkbp:contrastsWith programmed theories of aging
gptkbp:criticizedFor lack of direct evidence
gptkbp:effect increased risk of cancer
cellular dysfunction
tissue degeneration
gptkbp:field biology
gerontology
https://www.w3.org/2000/01/rdf-schema#label somatic mutation theory of aging
gptkbp:influencedBy radiation biology
gptkbp:involves genetic mutations
somatic cells
gptkbp:notableFigure gptkb:Leo_Szilard
gptkbp:originatedIn 1950s
gptkbp:proposedBy aging is caused by accumulation of mutations in somatic cells
gptkbp:relatedTo gptkb:DNA_damage_theory_of_aging
gptkb:mutation_accumulation_theory
gptkbp:bfsParent gptkb:DNA_damage_theory_of_aging
gptkbp:bfsLayer 7