Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
nuclear magnetic resonance spectroscopy
analytical technique |
| gptkbp:canBe |
gptkb:1D_NMR
gptkb:2D_NMR gptkb:3D_NMR gptkb:4D_NMR deuterated solvents external standards internal standards |
| gptkbp:commonExperiments |
gptkb:HMBC
gptkb:HSQC gptkb:NOESY gptkb:TOCSY gptkb:COSY |
| gptkbp:commonNuclei |
gptkb:15N
gptkb:1H gptkb:31P gptkb:19F 13C |
| gptkbp:detects |
nuclei with nonzero spin
nucleic acid structures in solution protein structures in solution small molecule structures |
| gptkbp:developedBy |
1940s
|
| gptkbp:format |
gptkb:FID_(free_induction_decay)
spectrum |
| https://www.w3.org/2000/01/rdf-schema#label |
solution NMR
|
| gptkbp:inventedBy |
gptkb:Edward_Purcell
gptkb:Felix_Bloch |
| gptkbp:limitation |
sensitive to temperature
limited for very large molecules requires relatively high sample concentration |
| gptkbp:measures |
relaxation times
chemical shifts coupling constants |
| gptkbp:provides |
information on molecular conformation
information on molecular dynamics information on molecular interactions |
| gptkbp:relatedTo |
MRI
solid-state NMR |
| gptkbp:requires |
strong magnetic field
radiofrequency pulses |
| gptkbp:usedFor |
analyzing chemical composition
determining molecular structure in solution studying dynamics of molecules |
| gptkbp:usedIn |
biochemistry
chemistry structural biology pharmaceutical research |
| gptkbp:uses |
liquid samples
|
| gptkbp:bfsParent |
gptkb:nuclear_magnetic_resonance_(NMR)
gptkb:NMR |
| gptkbp:bfsLayer |
6
|