Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cell_membrane
gptkb:enzyme ion pump |
| gptkbp:alsoKnownAs |
Na+/K+-ATPase
|
| gptkbp:discoveredBy |
gptkb:Jens_Christian_Skou
|
| gptkbp:discoveredIn |
1957
|
| gptkbp:encodedBy |
ATP1A1 gene (in humans)
|
| gptkbp:exportedTo |
sodium ions
|
| gptkbp:exportsNumber |
3 sodium ions per cycle
|
| gptkbp:foundIn |
animal cells
|
| gptkbp:function |
maintains sodium and potassium ion gradients across the plasma membrane
|
| https://www.w3.org/2000/01/rdf-schema#label |
sodium-potassium pump
|
| gptkbp:importantFor |
drives secondary active transport
maintains osmotic balance prevents cell swelling |
| gptkbp:imported |
potassium ions
|
| gptkbp:importsNumber |
2 potassium ions per cycle
|
| gptkbp:inhibitedBy |
gptkb:ouabain
digitalis |
| gptkbp:locatedIn |
gptkb:plasma_membrane
|
| gptkbp:mechanismOfAction |
active transport
|
| gptkbp:NobelPrizeYear |
Jens Christian Skou (1997, Chemistry)
|
| gptkbp:presentIn |
all animal cells
|
| gptkbp:requires |
resting membrane potential
cell volume regulation nerve impulse transmission |
| gptkbp:subunit |
alpha subunit
beta subunit gamma subunit |
| gptkbp:type |
P-type ATPase
|
| gptkbp:usesEnergyFrom |
ATP hydrolysis
|
| gptkbp:bfsParent |
gptkb:transport_proteins
|
| gptkbp:bfsLayer |
7
|