Properties (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hemophilia
|
| gptkbp:associatedWith |
hemarthrosis
muscle bleeds intracranial_hemorrhage |
| gptkbp:causedBy |
deficiency of clotting factor VIII
|
| gptkbp:clinicalTrials |
gene therapy trials
ongoing studies for new treatments factor replacement studies |
| gptkbp:demographics |
1 in 5,000 male births
|
| gptkbp:diseaseResistance |
blood tests
|
| gptkbp:educational_programs |
support groups
patient education materials medical professional training |
| gptkbp:emergencyServices |
requires access to clotting factor
requires immediate medical attention for bleeding |
| gptkbp:events |
gptkb:National_Hemophilia_Month
gptkb:World_Hemophilia_Day |
| gptkbp:geneticDiversity |
mutations in F8 gene
|
| gptkbp:hasPopulation |
can affect females in rare cases
primarily affects males |
| https://www.w3.org/2000/01/rdf-schema#label |
severe hemophilia
|
| gptkbp:impact |
improve quality of life
gene therapy desmopressin factor replacement therapy reduce complications prevent bleeding episodes |
| gptkbp:legalEvent |
normal with treatment
|
| gptkbp:manager |
prophylactic treatment
|
| gptkbp:nobleFamily |
X-linked recessive
|
| gptkbp:providesServices |
gptkb:World_Federation_of_Hemophilia
gptkb:National_Hemophilia_Foundation gptkb:Hemophilia_Federation_of_America |
| gptkbp:relatedPatent |
chronic pain
joint damage inhibitor development |
| gptkbp:researchFocus |
immunotherapy
gene editing new therapies |
| gptkbp:riskManagement |
genetic mutations
male gender family_history_of_hemophilia |
| gptkbp:screenings |
genetic testing
family history |
| gptkbp:symptoms |
joint pain
easy bruising excessive bleeding usually diagnosed in childhood |
| gptkbp:threats |
most_severe_form_of_hemophilia
|