serine racemase

GPTKB entity

Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activatedBy Mg2+
divalent cations
gptkbp:alternativeTo beta-elimination of water from L-serine to pyruvate
gptkbp:associatedWith schizophrenia
neurodegenerative diseases
gptkbp:catalyzes conversion of L-serine to D-serine
racemization of serine
gptkbp:cofactor gptkb:pyridoxal_phosphate
gptkbp:EC_number 5.1.1.18
gptkbp:expressedIn gptkb:kidney
central nervous system
liver
gptkbp:foundIn brain
neurons
astrocytes
gptkbp:gene gptkb:SRR
https://www.w3.org/2000/01/rdf-schema#label serine racemase
gptkbp:human_gene_location gptkb:chromosome_17
gptkbp:inhibitedBy gptkb:ATP
gptkb:AMP
gptkbp:involves glutamatergic neurotransmission
D-serine biosynthesis
gptkbp:orthologIn gptkb:mouse
gptkb:zebrafish
right
gptkbp:PDB 2ZPU
3L6B
gptkbp:regulates NMDA receptor activity
gptkbp:structure homodimer
gptkbp:UniProtID gptkb:O43175
gptkbp:bfsParent gptkb:D-serine
gptkb:pyridoxal_phosphate
gptkb:racemase
gptkbp:bfsLayer 7