Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternative_substrate |
glycine
alanine |
| gptkbp:catalyzes |
condensation of L-serine and palmitoyl-CoA
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
2.3.1.50
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:gene |
gptkb:SPTLC1
gptkb:SPTLC2 gptkb:SPTLC3 |
| gptkbp:inhibitedBy |
gptkb:myriocin
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
|
| gptkbp:mutationAssociatedWith |
gptkb:hereditary_sensory_and_autonomic_neuropathy_type_I
|
| gptkbp:pathway |
sphingolipid biosynthesis
|
| gptkbp:product |
gptkb:3-ketodihydrosphingosine
|
| gptkbp:subunit |
gptkb:SPTLC1
gptkb:SPTLC2 gptkb:SPTLC3 |
| gptkbp:systematicName |
gptkb:palmitoyl-CoA:L-serine_C-palmitoyltransferase_(decarboxylating)
|
| gptkbp:UniProtID |
Q16655 (human SPTLC1)
|
| gptkbp:bfsParent |
gptkb:pyridoxal_phosphate
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
serine palmitoyltransferase
|