samidorphan

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
opioid
gptkbp:approvedBy gptkb:FDA
2021
gptkbp:ATCCode N07AX32
gptkbp:brand gptkb:Lybalvi
gptkbp:CASNumber 197855-65-5
gptkbp:chemicalFormula C21H26N2O4
gptkbp:combines gptkb:olanzapine
gptkbp:developedBy gptkb:Alkermes
https://www.w3.org/2000/01/rdf-schema#label samidorphan
gptkbp:indication treatment of schizophrenia
treatment of bipolar I disorder
gptkbp:IUPACName 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one
gptkbp:legalStatus prescription only (Rx-only)
gptkbp:mechanismOfAction mu-opioid receptor antagonist
partial agonist at kappa- and delta-opioid receptors
gptkbp:molecularWeight 370.44 g/mol
gptkbp:routeOfAdministration oral
gptkbp:synonym ALKS-33
gptkbp:UNII 6Z5B6HVF6O
gptkbp:bfsParent gptkb:Lybalvi
gptkbp:bfsLayer 8