|
gptkbp:instanceOf
|
gptkb:drug
bisphosphonate
|
|
gptkbp:approvedBy
|
gptkb:FDA
gptkb:EMA
1998
|
|
gptkbp:ATCCode
|
M05BA07
|
|
gptkbp:brand
|
gptkb:Actonel
Atelvia
|
|
gptkbp:CASNumber
|
105462-24-6
|
|
gptkbp:chemicalClass
|
pyridinyl bisphosphonate
|
|
gptkbp:contraindication
|
hypocalcemia
esophageal abnormalities
inability to stand or sit upright for 30 minutes
|
|
gptkbp:discoveredBy
|
gptkb:Procter_&_Gamble
|
|
gptkbp:eliminationHalfLife
|
480 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:form
|
gptkb:tablet
delayed-release tablet
|
|
gptkbp:hasMolecularFormula
|
C7H11NO7P2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
risedronate
|
|
gptkbp:KEGGID
|
gptkb:D08402
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits osteoclast-mediated bone resorption
|
|
gptkbp:metabolism
|
not metabolized
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
CHEMBL1201192
52438
DB00884
|
|
gptkbp:riskFactor
|
osteonecrosis of the jaw
atypical femur fracture
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
abdominal pain
heartburn
esophageal irritation
|
|
gptkbp:UNII
|
YZO1F8A6F1
|
|
gptkbp:usedFor
|
gptkb:bone
gptkb:Paget's_disease_of_bone
|
|
gptkbp:bfsParent
|
gptkb:bisphosphonates
|
|
gptkbp:bfsLayer
|
6
|