Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
antiretroviral therapy
non-nucleoside reverse transcriptase inhibitor |
gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2011 |
gptkbp:ATCCode |
J05AG05
|
gptkbp:brand |
gptkb:Edurant
|
gptkbp:CASNumber |
500287-72-9
|
gptkbp:chemicalClass |
diarylpyrimidine
|
gptkbp:combinationTherapy |
gptkb:Complera
gptkb:Odefsey |
gptkbp:developedBy |
gptkb:Janssen_Pharmaceutica
|
gptkbp:eliminationHalfLife |
45 hours
|
gptkbp:hasMolecularFormula |
C22H18N6
|
https://www.w3.org/2000/01/rdf-schema#label |
rilpivirine
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
inhibits HIV-1 reverse transcriptase
|
gptkbp:metabolism |
liver (CYP3A4)
|
gptkbp:pregnancyCategory |
B (US)
B1 (Australia) |
gptkbp:proteinBinding |
99.7%
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
gptkb:depression
nausea headache rash insomnia |
gptkbp:usedFor |
HIV infection
|
gptkbp:bfsParent |
gptkb:NNRTIs
|
gptkbp:bfsLayer |
5
|