Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:antibiotic |
| gptkbp:ATCCode |
J01XX06
|
| gptkbp:CASNumber |
58-58-2
|
| gptkbp:category |
aminonucleoside antibiotic
|
| gptkbp:chemicalFormula |
C22H29N7O5
|
| gptkbp:discoveredBy |
Abraham, M. J.
|
| https://www.w3.org/2000/01/rdf-schema#label |
puromycin
|
| gptkbp:inhibitedBy |
peptidyl transferase activity
|
| gptkbp:mechanismOfAction |
causes premature chain termination during translation
|
| gptkbp:meltingPoint |
195-200 °C
|
| gptkbp:molecularWeight |
471.51 g/mol
|
| gptkbp:producedBy |
Streptomyces alboniger
|
| gptkbp:PubChem_CID |
2856
|
| gptkbp:relatedTo |
blasticidin S
cycloheximide |
| gptkbp:sideEffect |
proteinuria
nephrotoxicity |
| gptkbp:solubility |
soluble in water
|
| gptkbp:target |
ribosome
|
| gptkbp:UNII |
G3C28R6Z2E
|
| gptkbp:used_in |
molecular biology research
cell culture selection in vitro translation assays |
| gptkbp:usedFor |
protein synthesis inhibitor
selection of genetically engineered cells |
| gptkbp:bfsParent |
gptkb:Peptidyl_transferase
gptkb:Streptomyces gptkb:Amycolatopsis |
| gptkbp:bfsLayer |
7
|