Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:administeredBy |
inhalation
intravenous |
| gptkbp:alsoKnownAs |
gptkb:colistin
|
| gptkbp:ATCCode |
J01XB01
|
| gptkbp:CASNumber |
1264-72-8
|
| gptkbp:category |
polymyxin antibiotics
|
| gptkbp:chemicalFormula |
C53H100N16O13
|
| gptkbp:concerns |
mcr-1 gene
|
| gptkbp:discoveredBy |
Y. Koyama
|
| gptkbp:discoveredIn |
1949
|
| gptkbp:eliminatedIn |
renal
|
| https://www.w3.org/2000/01/rdf-schema#label |
polymyxin E
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
disrupts bacterial cell membrane
|
| gptkbp:producedBy |
gptkb:Paenibacillus_polymyxa
|
| gptkbp:sideEffect |
nephrotoxicity
neurotoxicity |
| gptkbp:spectrumOfActivity |
Gram-negative bacteria
|
| gptkbp:usedFor |
treatment of multidrug-resistant Gram-negative infections
|
| gptkbp:WHOStatus |
gptkb:World_Health_Organization_List_of_Essential_Medicines
|
| gptkbp:bfsParent |
gptkb:polymyxin
gptkb:colistin |
| gptkbp:bfsLayer |
8
|