Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
natural product
lignan |
| gptkbp:ATCCode |
D06BB04
|
| gptkbp:CASNumber |
518-28-5
|
| gptkbp:category |
metabolite
plant toxin antimitotic agent |
| gptkbp:chemicalFormula |
C22H22O8
|
| gptkbp:discoveredBy |
Georg Dragendorff
|
| gptkbp:discoveredIn |
1880
|
| gptkbp:foundIn |
gptkb:Podophyllum_hexandrum
gptkb:Podophyllum_peltatum Dysosma versipellis |
| https://www.w3.org/2000/01/rdf-schema#label |
podophyllotoxin
|
| gptkbp:IUPACName |
(5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-5,9-dihydroxy-2,5a,8,8a-tetramethyldibenzo[a,c]cycloocten-6-one
|
| gptkbp:mechanismOfAction |
inhibits microtubule assembly
|
| gptkbp:meltingPoint |
183–185 °C
|
| gptkbp:molecularWeight |
414.41 g/mol
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL418
10607 CHEBI:8053 DB01179 |
| gptkbp:relatedTo |
antineoplastic agent
teniposide |
| gptkbp:solubility |
insoluble in water
soluble in alcohol |
| gptkbp:toxicity |
toxic if ingested
|
| gptkbp:UNII |
X6XEA46401
|
| gptkbp:used_in_medicine |
treatment of external genital warts
|
| gptkbp:usedFor |
precursor for anticancer drugs
topical treatment for genital warts |
| gptkbp:bfsParent |
gptkb:antineoplastic_agent
|
| gptkbp:bfsLayer |
6
|