Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:activeIn |
gptkb:carbapenem-resistant_Enterobacteriaceae
gptkb:Enterobacteriaceae |
| gptkbp:administeredBy |
intravenous injection
|
| gptkbp:approvalYear |
2018
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
J01GB14
|
| gptkbp:brand |
gptkb:Zemdri
|
| gptkbp:chemicalFormula |
C25H43N5O10
|
| gptkbp:contraindication |
hypersensitivity to aminoglycosides
|
| gptkbp:developedBy |
gptkb:Achaogen
|
| gptkbp:eliminationHalfLife |
3.5 hours
|
| gptkbp:excretion |
gptkb:kidney
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits bacterial protein synthesis
|
| gptkbp:metabolism |
not significantly metabolized
|
| gptkbp:notEffectiveAgainst |
gptkb:Pseudomonas_aeruginosa
gptkb:Acinetobacter_baumannii |
| gptkbp:pregnancyCategory |
not recommended
|
| gptkbp:sideEffect |
diarrhea
hypertension nephrotoxicity ototoxicity |
| gptkbp:usedFor |
treatment of complicated urinary tract infections
|
| gptkbp:bfsParent |
gptkb:Achaogen
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
plazomicin
|