|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:activeIn
|
gptkb:carbapenem-resistant_Enterobacteriaceae
gptkb:Enterobacteriaceae
|
|
gptkbp:administeredBy
|
intravenous injection
|
|
gptkbp:approvalYear
|
2018
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J01GB14
|
|
gptkbp:brand
|
gptkb:Zemdri
|
|
gptkbp:chemicalFormula
|
C25H43N5O10
|
|
gptkbp:contraindication
|
hypersensitivity to aminoglycosides
|
|
gptkbp:developedBy
|
gptkb:Achaogen
|
|
gptkbp:eliminationHalfLife
|
3.5 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
plazomicin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial protein synthesis
|
|
gptkbp:metabolism
|
not significantly metabolized
|
|
gptkbp:notEffectiveAgainst
|
gptkb:Pseudomonas_aeruginosa
gptkb:Acinetobacter_baumannii
|
|
gptkbp:pregnancyCategory
|
not recommended
|
|
gptkbp:sideEffect
|
diarrhea
hypertension
nephrotoxicity
ototoxicity
|
|
gptkbp:usedFor
|
treatment of complicated urinary tract infections
|
|
gptkbp:bfsParent
|
gptkb:Achaogen
gptkb:Amycolatopsis
|
|
gptkbp:bfsLayer
|
7
|