Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biguanide drug
|
| gptkbp:ATCCode |
A10BA02
|
| gptkbp:CASNumber |
834-28-6
|
| gptkbp:category |
antidiabetic drug
|
| gptkbp:chemicalFormula |
C10H15N5
|
| gptkbp:discoveredBy |
gptkb:Jean_Sterne
|
| gptkbp:discoveredIn |
1957
|
| https://www.w3.org/2000/01/rdf-schema#label |
phenformin
|
| gptkbp:IUPACName |
2-phenylethylbiguanide
|
| gptkbp:legalStatus |
withdrawn in many countries
|
| gptkbp:mechanismOfAction |
increases insulin sensitivity
inhibits hepatic gluconeogenesis |
| gptkbp:molecularWeight |
205.26 g/mol
|
| gptkbp:relatedTo |
gptkb:metformin
buformin |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
gastrointestinal upset
lactic acidosis |
| gptkbp:usedFor |
gptkb:type_2_diabetes
|
| gptkbp:withdrawal_reason |
risk of lactic acidosis
|
| gptkbp:withdrawn |
yes
|
| gptkbp:bfsParent |
gptkb:AMPK_pathway
|
| gptkbp:bfsLayer |
6
|