Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
PT
whooping cough toxin |
| gptkbp:biologicalProcess |
ADP-ribosyltransferase activity
|
| gptkbp:cause |
increased cAMP levels
lymphocytosis |
| gptkbp:discoveredBy |
Margaret Pittman
|
| gptkbp:discoveredIn |
1940s
|
| gptkbp:encodedBy |
ptx operon
|
| gptkbp:foundIn |
Bordetella pertussis culture supernatant
|
| https://www.w3.org/2000/01/rdf-schema#label |
pertussis toxin
|
| gptkbp:mechanismOfAction |
inhibits G protein-coupled receptor signaling
|
| gptkbp:producedBy |
gptkb:Bordetella_pertussis
|
| gptkbp:role |
major virulence factor in whooping cough
|
| gptkbp:subunit |
gptkb:S1_subunit
gptkb:S2_subunit S3 subunit S4 subunit S5 subunit |
| gptkbp:target |
Gαi protein
|
| gptkbp:usedIn |
gptkb:acellular_pertussis_vaccine
|
| gptkbp:bfsParent |
gptkb:Bordetella_pertussis
|
| gptkbp:bfsLayer |
6
|