|
gptkbp:instanceOf
|
benzodiazepine
sedative
hypnotic
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
N05CA01
|
|
gptkbp:brand
|
gptkb:Nembutal
|
|
gptkbp:CASNumber
|
76-74-4
|
|
gptkbp:chemicalFormula
|
C11H18N2O3
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
porphyria
severe respiratory disease
|
|
gptkbp:discoveredBy
|
gptkb:Donalee_L._Tabern
gptkb:Ernest_H._Volwiler
|
|
gptkbp:discoveredIn
|
1930
|
|
gptkbp:drugClass
|
central nervous system depressant
|
|
gptkbp:eliminationHalfLife
|
15-50 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:flavor
|
slightly bitter
|
|
gptkbp:form
|
crystalline powder
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pentobarbital
|
|
gptkbp:IUPACName
|
5-ethyl-5-(1-methylbutyl)-1,3-diazinane-2,4,6-trione
|
|
gptkbp:legalStatus
|
gptkb:Schedule_II_(US)
Schedule IV (CA)
|
|
gptkbp:mechanismOfAction
|
GABAA receptor positive allosteric modulator
|
|
gptkbp:medicalUse
|
preanesthetic
emergency control of seizures
short-term treatment of insomnia
|
|
gptkbp:meltingPoint
|
129–130 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
226.28 g/mol
|
|
gptkbp:overdoseSymptoms
|
death
coma
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:PubChem_CID
|
CHEMBL504
4737
4575
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
drowsiness
hypotension
respiratory depression
dependence
|
|
gptkbp:solubility
|
1 g/100 mL
|
|
gptkbp:synonym
|
gptkb:Nembutal
gptkb:pentobarbitone
|
|
gptkbp:UNII
|
K7Q1JQR04M
|
|
gptkbp:usedFor
|
assisted suicide
lethal injection
animal euthanasia
|
|
gptkbp:bfsParent
|
gptkb:4-aminobutanoic_acid
|
|
gptkbp:bfsLayer
|
6
|