|
gptkbp:instanceOf
|
gptkb:amino_acid_derivative
gptkb:drug
gptkb:chelating_agent
|
|
gptkbp:ATCCode
|
M01CC01
|
|
gptkbp:CASNumber
|
52-67-5
|
|
gptkbp:category
|
gptkb:amino_acid_transporter
gptkb:WHO_essential_medicines
gptkb:antidote
gptkb:organosulfur_compound
chelator
antirheumatic agent
thiol compound
|
|
gptkbp:chemicalFormula
|
C5H11NO2S
|
|
gptkbp:contraindication
|
pregnancy
renal impairment
|
|
gptkbp:derivedFrom
|
gptkb:antibiotic
|
|
gptkbp:discoveredBy
|
John Walshe
|
|
gptkbp:discoveredIn
|
1956
|
|
gptkbp:eliminationHalfLife
|
1-7 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:IUPACName
|
(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
|
|
gptkbp:KEGGID
|
D08367
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
reduces cystine stone formation
immunomodulatory effects
chelates heavy metals
|
|
gptkbp:meltingPoint
|
212–215 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
149.21 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:PubChem_CID
|
4676
CHEMBL1425
CHEBI:7943
DB00859
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
aplastic anemia
autoimmune disorders
proteinuria
rash
leukopenia
|
|
gptkbp:synonym
|
3-mercapto-D-valine
D-penicillamine
beta,beta-dimethylcysteine
|
|
gptkbp:UNII
|
9H3C539U1D
|
|
gptkbp:usedFor
|
gptkb:Wilson's_disease
rheumatoid arthritis
cystinuria
|
|
gptkbp:bfsParent
|
gptkb:Cuprimine
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
penicillamine
|