pegfilgrastim

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkb:granulocyte_colony-stimulating_factor
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
2002
gptkbp:ATCCode L03AA13
gptkbp:biosimilar yes
gptkbp:brand gptkb:Neulasta
gptkbp:CASNumber 208265-92-3
gptkbp:chemicalClass pegylated protein
gptkbp:contraindication hypersensitivity to pegfilgrastim
gptkbp:developedBy gptkb:Amgen
gptkbp:eliminationHalfLife 15-80 hours
gptkbp:hasMolecularFormula C845H1343N223O243S9
https://www.w3.org/2000/01/rdf-schema#label pegfilgrastim
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction stimulates production of neutrophils
gptkbp:pegylated yes
gptkbp:pregnancyCategory C (US)
gptkbp:product recombinant human G-CSF
gptkbp:routeOfAdministration subcutaneous injection
gptkbp:sideEffect bone pain
allergic reactions
splenic rupture
gptkbp:UNII 6X8X110A8H
gptkbp:usedFor chemotherapy-induced neutropenia
prevention of neutropenia
gptkbp:bfsParent gptkb:Neulasta
gptkbp:bfsLayer 7