|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:administeredBy
|
oral
intramuscular injection
|
|
gptkbp:ATCCode
|
gptkb:A07AA06
|
|
gptkbp:brand
|
gptkb:Humatin
gptkb:Paromycin
|
|
gptkbp:CASNumber
|
7542-37-2
|
|
gptkbp:contraindication
|
intestinal obstruction
hypersensitivity to aminoglycosides
|
|
gptkbp:discoveredBy
|
gptkb:Herbert_E._Carter
|
|
gptkbp:discoveredIn
|
1956
|
|
gptkbp:eliminatedIn
|
urine
|
|
gptkbp:eliminationHalfLife
|
5 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C23H45N5O14
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
paromomycin
|
|
gptkbp:KEGGID
|
D08367
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits protein synthesis by binding to 16S rRNA of the 30S ribosomal subunit
|
|
gptkbp:meltingPoint
|
220°C (decomposes)
|
|
gptkbp:MeSH_ID
|
D010273
|
|
gptkbp:pregnancyCategory
|
C
|
|
gptkbp:PubChem_CID
|
390006
441375
CHEMBL1201207
DB01421
|
|
gptkbp:sideEffect
|
nausea
diarrhea
nephrotoxicity
abdominal cramps
ototoxicity
|
|
gptkbp:UNII
|
T5V8U2JKHF
|
|
gptkbp:usedFor
|
leishmaniasis
amebiasis
cryptosporidiosis
giardiasis
intestinal infections
tapeworm infection
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Leishmania_donovani
gptkb:Leishmaniasis
|
|
gptkbp:bfsLayer
|
5
|