Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:antibiotic |
| gptkbp:ATCCode |
J04AA01
|
| gptkbp:CASNumber |
65-49-6
|
| gptkbp:category |
antitubercular agents
salicylic acids |
| gptkbp:chemicalFormula |
C7H7NO3
|
| gptkbp:discoveredBy |
gptkb:Jörgen_Lehmann
|
| gptkbp:discoveredIn |
1944
|
| https://www.w3.org/2000/01/rdf-schema#label |
para-aminosalicylic acid
|
| gptkbp:IUPACName |
4-aminosalicylic acid
|
| gptkbp:mechanismOfAction |
inhibits folic acid synthesis in Mycobacterium tuberculosis
|
| gptkbp:meltingPoint |
150°C
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
hepatitis
gastrointestinal upset hypersensitivity reactions |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:synonym |
gptkb:PAS
4-aminosalicylic acid |
| gptkbp:usedFor |
treatment of tuberculosis
|
| gptkbp:bfsParent |
gptkb:Sir_John_Crofton_method
|
| gptkbp:bfsLayer |
7
|