Statements (69)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
4
|
| gptkbp:bfsParent |
gptkb:TFIIH
|
| gptkbp:associated_with |
mitogen-activated protein kinase
|
| gptkbp:code |
MAP K14 gene
|
| gptkbp:defense_mechanism |
inflammation response
|
| gptkbp:established |
growth factors
specific inhibitors |
| gptkbp:function |
regulating cell growth
|
| gptkbp:has_role |
cell proliferation
stress response |
| https://www.w3.org/2000/01/rdf-schema#label |
p44 subunit
|
| gptkbp:interacts_with |
other kinases
p42 subunit |
| gptkbp:is_a_route_for |
insulin signaling
|
| gptkbp:is_aimed_at |
therapeutic agents
|
| gptkbp:is_associated_with |
cell differentiation
cellular homeostasis cellular stress response cell survival cellular signaling dynamics |
| gptkbp:is_essential_for |
cellular response to stimuli
|
| gptkbp:is_found_in |
cytoplasm
|
| gptkbp:is_involved_in |
apoptosis regulation
cell cycle regulation cell signaling immune response wound healing neuroinflammation cardiovascular diseases tumorigenesis oxidative stress neuroprotection cell migration signal amplification cellular repair mechanisms metabolic regulation |
| gptkbp:is_known_for |
modulate gene expression
influence cell fate a key regulator affect cellular functions modulate inflammation |
| gptkbp:is_linked_to |
gptkb:psychologist
metabolic disorders autoimmune diseases chronic diseases cancer progression |
| gptkbp:is_part_of |
gptkb:MAPK/_ERK_signaling_complex
signal transduction pathways cellular machinery MAPK signaling cascade protein complexes cellular response pathways |
| gptkbp:is_represented_in |
gptkb:smartphone
gptkb:embryonic_development various tissues cancer cells |
| gptkbp:is_studied_in |
aging
drug development therapeutic interventions biomedical research pharmacology. |
| gptkbp:network |
cellular signaling network
|
| gptkbp:part_of |
p44/p42 MAPK pathway
|
| gptkbp:regulates |
Ras signaling pathway
phosphorylation |
| gptkbp:related_to |
gptkb:extracellular_signal-regulated_kinase
|
| gptkbp:type_of |
gptkb:microprocessor
|
| gptkbp:weight |
approximately 44 k Da
|