Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
biomarker |
gptkbp:chemicalFormula |
C20H32N6O12S2
|
gptkbp:contains_functional_group |
disulfide bond
|
gptkbp:foundIn |
gptkb:endoplasmic_reticulum
cells mitochondria blood plasma cytosol |
gptkbp:hasRole |
antioxidant
redox buffer |
https://www.w3.org/2000/01/rdf-schema#label |
oxidized glutathione
|
gptkbp:importantFor |
detoxification of reactive oxygen species
protection against oxidative stress protein S-glutathionylation |
gptkbp:involves |
cellular redox homeostasis
glutathione-ascorbate cycle |
gptkbp:is_oxidized_form_of |
glutathione
|
gptkbp:is_reduced_to |
glutathione (GSH)
|
gptkbp:IUPACName |
(2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid disulfide
|
gptkbp:measures |
GSSG/GSH ratio
|
gptkbp:molecularWeight |
612.63 g/mol
|
gptkbp:otherName |
GSSG
|
gptkbp:producedBy |
oxidation of glutathione (GSH)
|
gptkbp:product |
glutathione peroxidase
|
gptkbp:substrate |
glutathione reductase
|
gptkbp:bfsParent |
gptkb:Glutathione_peroxidase
|
gptkbp:bfsLayer |
7
|