organ-on-a-chip

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf gptkb:biotechnology
microfluidic cell culture device
gptkbp:advantage real-time monitoring
dynamic microenvironment
human-relevant data
reduced animal use
gptkbp:alternativeTo animal testing
gptkbp:component biomaterials
sensors
membranes
living cells
microchannels
gptkbp:developedBy gptkb:Donald_Ingber
gptkb:Wyss_Institute_for_Biologically_Inspired_Engineering
gptkbp:enables precision medicine
personalized medicine
disease modeling
high-throughput screening
mechanistic studies
gptkbp:field gptkb:biotechnology
gptkb:pharmacy
biomedical engineering
tissue engineering
toxicology
drug discovery
regenerative medicine
microfluidics
gptkbp:firstDescribed 2010
gptkbp:fundedBy gptkb:DARPA
gptkb:FDA
gptkb:NIH
gptkbp:hasPatent US20120214200A1
https://www.w3.org/2000/01/rdf-schema#label organ-on-a-chip
gptkbp:limitation standardization
scalability
complexity
gptkbp:relatedTo gptkb:lab-on-a-chip
microphysiological system
organoid
gptkbp:SIM gptkb:cancer
gptkb:skin
gptkb:kidney
brain
heart
liver
gut
gptkbp:usedFor toxicology studies
disease modeling
drug testing
simulating organ functions
gptkbp:bfsParent gptkb:Wyss_Institute_for_Biologically_Inspired_Engineering
gptkbp:bfsLayer 5