oral polio vaccine (OPV)

GPTKB entity

Statements (43)
Predicate Object
gptkbp:instance_of gptkb:vaccine
gptkbp:administered_by oral route
gptkbp:administration_age administered to infants
gptkbp:associated_with gptkb:virus
gptkbp:availability widely available in developing countries
gptkbp:clinical_trial extensively tested in clinical trials
gptkbp:community_acceptance high community acceptance in many regions
gptkbp:community_health significantly reduced polio cases
gptkbp:contraindication immunocompromised individuals
gptkbp:developed_by gptkb:Albert_Bruce_Sabin
gptkbp:dose_schedule multiple doses required
gptkbp:first_introduced gptkb:Soviet_Union
gptkbp:formulation drops
gptkbp:global_presence used in over 100 countries
gptkbp:history developed in the 1950s
https://www.w3.org/2000/01/rdf-schema#label oral polio vaccine (OPV)
gptkbp:immunization_strategy part of global polio eradication initiative
gptkbp:introduced_in gptkb:1961
gptkbp:is_effective_against high efficacy in preventing polio
gptkbp:is_recommended_by gptkb:World_Health_Organization
gptkbp:is_vulnerable_to oral polio vaccine
high coverage in immunization programs
some vaccine hesitancy reported
gptkbp:manufacturer various pharmaceutical companies
gptkbp:mechanism_of_action induces intestinal immunity
gptkbp:part_of expanded program on immunization (EPI)
gptkbp:price low-cost vaccine
gptkbp:provides_immunity long-term immunity
gptkbp:public_perception generally positive perception
gptkbp:regulatory_compliance approved by health authorities
gptkbp:replaced_by inactivated polio vaccine (IPV) in some countries
gptkbp:research_focus ongoing research for improved formulations
gptkbp:safety_features generally safe
gptkbp:side_effect mild gastrointestinal symptoms
gptkbp:storage refrigeration not required
gptkbp:success_rate high success rate in outbreak control
gptkbp:supply_chain requires cold chain for distribution
gptkbp:targets gptkb:poliomyelitis
gptkbp:type live attenuated vaccine
gptkbp:used_in mass immunization campaigns
gptkbp:bfsParent gptkb:first_effective_polio_vaccine
gptkb:inactivated_polio_vaccine_(IPV)
gptkbp:bfsLayer 7