ofloxacin

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:antibiotic
fluoroquinolone
gptkbp:approvedBy 1985
gptkbp:ATCCode J01MA01
gptkbp:brand Floxin
Oflox
Tarivid
gptkbp:CASNumber 82419-36-1
gptkbp:contraindication children
pregnancy
hypersensitivity to quinolones
gptkbp:discoveredBy gptkb:Daiichi_Sankyo
gptkbp:eliminationHalfLife 4-5 hours
gptkbp:excretion urine
gptkbp:hasMolecularFormula C18H20FN3O4
https://www.w3.org/2000/01/rdf-schema#label ofloxacin
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibits DNA gyrase
inhibits topoisomerase IV
gptkbp:metabolism liver
gptkbp:pregnancyCategory C (US)
gptkbp:routeOfAdministration oral
topical
intravenous
gptkbp:sideEffect nausea
diarrhea
dizziness
headache
insomnia
gptkbp:usedFor gptkb:prostatitis
skin infections
urinary tract infections
gonorrhea
bacterial infections
respiratory tract infections
gptkbp:bfsParent gptkb:Fluoroquinolones
gptkbp:bfsLayer 5