Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:neurofibromatosis
|
| gptkbp:affects |
gptkb:computer
|
| gptkbp:associated_with |
other tumors
schwannomas meningiomas bilateral vestibular schwannomas ependymomas |
| gptkbp:cause |
tumors
|
| gptkbp:clinical_trial |
variable expressivity
age of onset variability multiple tumors bilateral tumors penetrance |
| gptkbp:complications |
psychosocial issues
neurological deficits surgery risks |
| gptkbp:condition |
gptkb:neurofibromatosis_type_1
|
| gptkbp:diagnosis |
early adulthood
adolescence MRI scan |
| gptkbp:first_described_by |
1930s
|
| gptkbp:genetic_studies |
available
recommended for family members |
| https://www.w3.org/2000/01/rdf-schema#label |
neurofibromatosis type 2
|
| gptkbp:inherits_from |
autosomal dominant
|
| gptkbp:is_a_basis_for |
NF2 gene mutation
|
| gptkbp:is_involved_in |
online communities
NF2 Foundation |
| gptkbp:prevalence |
1 in 25,000
|
| gptkbp:public_awareness |
Neurofibromatosis Awareness Month
|
| gptkbp:research_focus |
gptkb:gene_therapy
clinical trials |
| gptkbp:research_institutes |
gptkb:Mayo_Clinic
gptkb:Johns_Hopkins_University gptkb:National_Institutes_of_Health |
| gptkbp:risk_factor |
family history
genetic predisposition |
| gptkbp:symptoms |
hearing loss
cataracts balance issues tinnitus skin tumors spinal tumors |
| gptkbp:treatment |
gptkb:pharmaceuticals
gptkb:surgery symptomatic treatment monitoring radiation therapy clinical management |
| gptkbp:bfsParent |
gptkb:sarcophagus
gptkb:neurofibromatosis |
| gptkbp:bfsLayer |
5
|