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gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alsoKnownAs
|
gptkb:CK-MM
creatine kinase M-type
|
|
gptkbp:assay
|
CK-MM blood test
|
|
gptkbp:cofactor
|
Mg2+
|
|
gptkbp:discoveredBy
|
Otto Lohmann
|
|
gptkbp:discoveredIn
|
1927
|
|
gptkbp:EC_number
|
2.7.3.2
|
|
gptkbp:encodedBy
|
gptkb:CKM_gene
|
|
gptkbp:Entrez_Gene_ID
|
1158
|
|
gptkbp:form
|
homodimer
heterodimer with CK-BB
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
cardiac muscle
|
|
gptkbp:function
|
catalyzes transfer of phosphate from ATP to creatine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
muscle creatine kinase
|
|
gptkbp:inhibitedBy
|
creatine analogs
|
|
gptkbp:molecularWeight
|
about 86 kDa (dimer)
|
|
gptkbp:OMIM
|
123320
|
|
gptkbp:pathway
|
energy metabolism
|
|
gptkbp:product
|
gptkb:ADP
gptkb:phosphocreatine
|
|
gptkbp:relatedTo
|
myocardial infarction
muscular dystrophy
rhabdomyolysis
|
|
gptkbp:significance
|
elevated in muscle damage
used as marker for myocardial infarction
|
|
gptkbp:structure
|
dimeric protein
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
|
|
gptkbp:substrate
|
gptkb:ATP
gptkb:creatine
|
|
gptkbp:tissue_specificity
|
predominant in muscle tissue
|
|
gptkbp:UniProtID
|
P06732
|
|
gptkbp:bfsParent
|
gptkb:MyoD
|
|
gptkbp:bfsLayer
|
7
|