multiple endocrine neoplasia syndrome type 2
GPTKB entity
Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:item
|
| gptkbp:associated_with |
gptkb:medullary_thyroid_carcinoma
gptkb:pheochromocytoma primary hyperparathyroidism |
| gptkbp:caused_by |
gptkb:RET_gene_mutation
|
| gptkbp:current_use |
gptkb:neurofibromatosis_type_1
gptkb:Von_Hippel-Lindau_disease |
| gptkbp:descendant |
autosomal dominant
|
| gptkbp:first_described_by |
in the 20th century
|
| gptkbp:genetic_diversity |
for family members of affected individuals
|
| https://www.w3.org/2000/01/rdf-schema#label |
multiple endocrine neoplasia syndrome type 2
|
| gptkbp:is_popular_in |
rare
|
| gptkbp:premiered_on |
childhood to early adulthood
|
| gptkbp:risk_factor |
family history
|
| gptkbp:screenings |
early screening for at-risk individuals
|
| gptkbp:social_responsibility |
genetic testing
variable depending on type and treatment |
| gptkbp:symptoms |
gptkb:historical_event
gptkb:neuroblastoma gptkb:gastrinoma gptkb:glucagonomas gptkb:insulinomas gptkb:medullary_thyroid_carcinoma gptkb:somatostatinomas anxiety dizziness fatigue nausea hypertension weight loss abdominal pain vomiting diarrhea muscle weakness excessive sweating headaches bone pain palpitations kidney stones hypercalcemia skin changes flushing gastrointestinal issues neuroendocrine tumors acromegaly thyroid nodules neck mass vision changes hearing changes parathyroid adenomas adrenal tumors VI Pomas cushing's syndrome |
| gptkbp:treatment |
surgical removal of tumors
medication for symptom management |
| gptkbp:type_of |
MEN 2 A
MEN 2 B |
| gptkbp:bfsParent |
gptkb:Trulicity
gptkb:Tirzepatide |
| gptkbp:bfsLayer |
4
|