Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
peptide
synthetic antineoplastic agent |
| gptkbp:ATCCode |
L01XC32
|
| gptkbp:CASNumber |
646502-53-6
|
| gptkbp:derivedFrom |
dolastatin 10
|
| gptkbp:discoveredBy |
gptkb:Seattle_Genetics
|
| gptkbp:hasMolecularFormula |
C39H67N5O7
|
| https://www.w3.org/2000/01/rdf-schema#label |
monomethyl auristatin E
|
| gptkbp:inhibitedBy |
tubulin polymerization
|
| gptkbp:mechanismOfAction |
microtubule inhibitor
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nausea
fatigue peripheral neuropathy neutropenia |
| gptkbp:synonym |
MMAE
|
| gptkbp:usedFor |
gptkb:cancer
|
| gptkbp:usedIn |
gptkb:brentuximab_vedotin
antibody-drug conjugates polatuzumab vedotin |
| gptkbp:bfsParent |
gptkb:brentuximab_vedotin
|
| gptkbp:bfsLayer |
7
|