methotrimeprazine

GPTKB entity

Statements (41)
Predicate Object
gptkbp:instanceOf gptkb:drug
phenothiazine derivative
gptkbp:administeredBy palliative care
end-of-life care
gptkbp:ATCCode N05AA02
gptkbp:availableOn gptkb:tablet
injectable solution
gptkbp:brand gptkb:Nozinan
gptkbp:CASNumber 60-04-4
gptkbp:category analgesic
antipsychotic medication
antiemetic
gptkbp:chemicalFormula C18H24N2OS
gptkbp:contraindication bone marrow depression
severe CNS depression
hypersensitivity to phenothiazines
gptkbp:discoveredBy gptkb:Rhodia
gptkbp:discoveredIn 1950s
gptkbp:eliminationHalfLife 15-30 hours
https://www.w3.org/2000/01/rdf-schema#label methotrimeprazine
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction antihistamine
dopamine receptor antagonist
anticholinergic
alpha-adrenergic blocker
gptkbp:metabolism liver
gptkbp:pregnancyCategory gptkb:C_(Australia)
gptkbp:routeOfAdministration oral
intramuscular
intravenous
gptkbp:sideEffect hypotension
sedation
extrapyramidal symptoms
anticholinergic effects
gptkbp:synonym levomepromazine
gptkbp:usedFor nausea
schizophrenia
pain management
agitation
gptkbp:bfsParent gptkb:Levomepromazine
gptkbp:bfsLayer 7