Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:affiliatedWith |
aminoacyl-tRNA synthetase family
|
| gptkbp:alternativeName |
MARS
MetRS |
| gptkbp:associatedWith |
Charcot-Marie-Tooth disease (some forms)
|
| gptkbp:catalyzes |
attachment of methionine to tRNA^Met
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:EC_number |
6.1.1.10
|
| gptkbp:foundIn |
gptkb:cytoplasm
mitochondria |
| gptkbp:function |
protein biosynthesis
|
| gptkbp:gene |
MARS (in humans)
|
| gptkbp:GO_term |
GO:0004825
|
| https://www.w3.org/2000/01/rdf-schema#label |
methionyl-tRNA synthetase
|
| gptkbp:organism |
present in all domains of life
|
| gptkbp:product |
gptkb:AMP
pyrophosphate methionyl-tRNA^Met |
| gptkbp:requires |
elongation of translation
initiation of translation |
| gptkbp:structure |
homodimer (in many species)
|
| gptkbp:substrate |
gptkb:ATP
methionine tRNA^Met |
| gptkbp:UniProtID |
P56192 (human cytoplasmic)
P56192 (human mitochondrial) |
| gptkbp:bfsParent |
gptkb:class_I_aminoacyl-tRNA_synthetase
|
| gptkbp:bfsLayer |
7
|