Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:methionine_gamma-lyase
gptkb:MGL |
| gptkbp:catalyzes |
L-methionine to methanethiol, ammonia, and 2-oxobutanoate
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
4.4.1.11
|
| gptkbp:foundIn |
gptkb:Trichomonas_vaginalis
gptkb:Pseudomonas_putida |
| gptkbp:gene |
mdeA (in Pseudomonas putida)
|
| https://www.w3.org/2000/01/rdf-schema#label |
methioninase
|
| gptkbp:inhibitedBy |
hydrogen peroxide
heavy metals methionine metabolism |
| gptkbp:molecularWeight |
~172 kDa (tetrameric form)
|
| gptkbp:optimum_pH |
37°C
7.0-8.0 |
| gptkbp:produces |
ammonia
methanethiol 2-oxobutanoate |
| gptkbp:structure |
homotetramer
|
| gptkbp:systematicName |
L-methionine methanethiol-lyase (deaminating)
|
| gptkbp:used_in |
biocatalysis
cancer therapy research biotechnological applications |
| gptkbp:bfsParent |
gptkb:methionine_gamma-lyase
|
| gptkbp:bfsLayer |
8
|