|
gptkbp:instanceOf
|
gptkb:drug
anti-inflammatory agent
|
|
gptkbp:affiliatedWith
|
aminosalicylates
|
|
gptkbp:alsoKnownAs
|
mesalamine
5-aminosalicylic acid
|
|
gptkbp:ATCCode
|
A07EC02
|
|
gptkbp:CASNumber
|
89-57-6
|
|
gptkbp:chemicalFormula
|
C7H7NO3
|
|
gptkbp:color
|
white to pinkish crystalline powder
|
|
gptkbp:contraindication
|
hypersensitivity to salicylates
|
|
gptkbp:discoveredBy
|
Karel Stokvis
|
|
gptkbp:discoveredIn
|
1942
|
|
gptkbp:eliminationHalfLife
|
0.5 to 1.5 hours
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mesalazine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits cyclooxygenase and lipoxygenase pathways
|
|
gptkbp:meltingPoint
|
280°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
153.14 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
4075
DB00244
|
|
gptkbp:routeOfAdministration
|
oral
rectal
|
|
gptkbp:sideEffect
|
nausea
diarrhea
abdominal pain
headache
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:UNII
|
4Q81I59GXC
|
|
gptkbp:usedFor
|
gptkb:Crohn's_disease
ulcerative colitis
|
|
gptkbp:bfsParent
|
gptkb:Asacol
|
|
gptkbp:bfsLayer
|
7
|