long-term evolution experiment
GPTKB entity
Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
scientific research
|
| gptkbp:descendedFrom |
gptkb:E._coli_B_strain_REL606
|
| gptkbp:duration |
over 75,000 generations
|
| gptkbp:fundedBy |
gptkb:National_Institutes_of_Health
gptkb:National_Science_Foundation |
| https://www.w3.org/2000/01/rdf-schema#label |
long-term evolution experiment
|
| gptkbp:launched |
gptkb:Richard_Lenski
|
| gptkbp:location |
gptkb:Michigan_State_University
|
| gptkbp:mediaType |
minimal glucose medium
|
| gptkbp:method |
daily serial transfer
|
| gptkbp:notableAchievement |
demonstrated repeatability and contingency in evolution
evidence for clonal interference evidence for epistasis evolution of adaptation to laboratory environment evolution of antagonistic pleiotropy evolution of cell size evolution of compensatory mutations evolution of ecological interactions evolution of fitness trade-offs evolution of gene duplications evolution of genetic drift effects evolution of genetic robustness evolution of genome reduction evolution of genomic deletions evolution of growth rate evolution of insertion sequence activity evolution of metabolic pathways evolution of mutation rates evolution of mutator phenotypes evolution of novel traits evolution of pleiotropy evolution of point mutations evolution of population dynamics evolution of regulatory changes evolution of stress resistance genetic divergence among populations increased fitness over time parallel evolution observed |
| gptkbp:notableFinds |
evolution of citrate metabolism
|
| gptkbp:numberOfPopulations |
12
|
| gptkbp:organism |
gptkb:Bacteria
|
| gptkbp:publishedIn |
gptkb:Blount_ZD_et_al.,_2008,_PNAS
gptkb:Lenski_RE_et_al.,_1991,_Science |
| gptkbp:purpose |
study evolution in real time
|
| gptkbp:sampleInterval |
every 500 generations
|
| gptkbp:startDate |
February 24, 1988
|
| gptkbp:type |
genomic sequencing
frozen samples |
| gptkbp:website |
https://lenski.mmg.msu.edu/ltee/
|
| gptkbp:bfsParent |
gptkb:Jeffrey_E._Barrick
|
| gptkbp:bfsLayer |
6
|