Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
beta-secretase inhibitor |
| gptkbp:ATCCode |
none (not assigned)
|
| gptkbp:CASNumber |
1262414-35-6
|
| gptkbp:clinicalTrialPhase |
terminated
Phase III |
| gptkbp:developedBy |
gptkb:AstraZeneca
gptkb:Eli_Lilly_and_Company |
| gptkbp:endDate |
lack of efficacy
|
| https://www.w3.org/2000/01/rdf-schema#label |
lanabecestat
|
| gptkbp:intendedUse |
treatment of Alzheimer's disease
|
| gptkbp:mechanismOfAction |
inhibits beta-secretase 1 (BACE1)
|
| gptkbp:PubChem_CID |
71587661
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:status |
investigational
|
| gptkbp:synonym |
AZD3293
LY3314814 |
| gptkbp:target |
gptkb:BACE1
|
| gptkbp:bfsParent |
gptkb:BACE1
|
| gptkbp:bfsLayer |
8
|