ketamine

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instanceOf gptkb:drug
NMDA receptor antagonist
dissociative anesthetic
gptkbp:abusePotential moderate
gptkbp:approvedBy 1970 (US)
gptkbp:ATCCode gptkb:N01AX03
gptkbp:brand gptkb:Ketalar
gptkb:Ketanest
gptkb:Ketaset
gptkb:Ketavet
gptkbp:CASNumber 6740-88-1
gptkbp:chemicalFormula C13H16ClNO
gptkbp:contraindication history of psychosis
severe hypertension
gptkbp:discoveredBy gptkb:Calvin_Stevens
gptkbp:discoveredIn 1962
gptkbp:eliminationHalfLife 2.5-3 hours
gptkbp:excretion urine
gptkbp:hasEnantiomer gptkb:arketamine
gptkb:esketamine
https://www.w3.org/2000/01/rdf-schema#label ketamine
gptkbp:IUPACName (RS)-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone
gptkbp:legalStatus gptkb:Schedule_III_(US)
Prescription only (various countries)
gptkbp:mainStreet gptkb:Kit_Kat
gptkb:Vitamin_K
gptkb:Special_K
K
gptkbp:mechanismOfAction NMDA receptor antagonism
interaction with monoaminergic receptors
interaction with opioid receptors
gptkbp:metabolism liver
gptkbp:molecularWeight 237.725 g/mol
gptkbp:pregnancyCategory B (US)
gptkbp:PubChem_CID gptkb:CHEMBL402
3821
gptkbp:routeOfAdministration oral
intramuscular
intravenous
intranasal
gptkbp:sideEffect confusion
nausea
dissociation
hallucinations
elevated blood pressure
gptkbp:UNII 690G0D6V8H
gptkbp:usedFor pain management
treatment-resistant depression
anesthesia
status epilepticus
sedation
gptkbp:usedIn gptkb:veterinary_medicine
gptkbp:bfsParent gptkb:memantine
gptkbp:bfsLayer 5