hypoxanthine-guanine phosphoribosyltransferase
GPTKB entity
Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
HGPRT
|
| gptkbp:associatedWith |
gout
|
| gptkbp:biologicalProcess |
purine salvage pathway
|
| gptkbp:CASNumber |
9030-21-1
|
| gptkbp:catalyzes |
conversion of guanine to GMP
conversion of hypoxanthine to IMP |
| gptkbp:deficiencyCauses |
gptkb:Lesch-Nyhan_syndrome
|
| gptkbp:EC_number |
2.4.2.8
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:gene |
HPRT1
|
| gptkbp:GO_term |
GO:0004422
|
| https://www.w3.org/2000/01/rdf-schema#label |
hypoxanthine-guanine phosphoribosyltransferase
|
| gptkbp:locatedOnChromosome |
Xq26.1
|
| gptkbp:OMIM |
308000
|
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
phosphoribosyl pyrophosphate (PRPP)
|
| gptkbp:UniProtID |
P00492
|
| gptkbp:bfsParent |
gptkb:Lesch–Nyhan_syndrome
|
| gptkbp:bfsLayer |
7
|