Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:HSA
|
| gptkbp:alternativeName |
gptkb:ALB
gptkb:serum_albumin albumin |
| gptkbp:binds |
gptkb:water
copper zinc drugs calcium thyroid hormones fatty acids bilirubin steroid hormones |
| gptkbp:concentrationInPlasma |
35-50 g/L
|
| gptkbp:degradedBy |
gptkb:kidney
liver |
| gptkbp:discoveredBy |
Friedrich Hoppe-Seyler
|
| gptkbp:discoveredIn |
1864
|
| gptkbp:encodedBy |
gptkb:ALB_gene
|
| gptkbp:foundIn |
human blood plasma
|
| gptkbp:function |
maintains oncotic pressure
transports bilirubin transports drugs transports fatty acids transports hormones |
| gptkbp:glycosylation |
non-glycosylated
|
| gptkbp:halfLife |
about 19 days
|
| https://www.w3.org/2000/01/rdf-schema#label |
human serum albumin
|
| gptkbp:locatedOnChromosome |
4q13.3
|
| gptkbp:mainIngredient |
can cause allergic reactions in rare cases
|
| gptkbp:medicalUse |
treatment of burns
treatment of hypoalbuminemia treatment of shock volume expander |
| gptkbp:molecularWeight |
about 66.5 kDa
|
| gptkbp:PDB |
gptkb:1AO6
|
| gptkbp:pI |
4.7
|
| gptkbp:solubility |
highly soluble in water
|
| gptkbp:stable |
blood volume
stable at physiological pH |
| gptkbp:structure |
single polypeptide chain
|
| gptkbp:synthesisType |
liver
|
| gptkbp:UniProtID |
gptkb:P02768
|
| gptkbp:usedIn |
laboratory diagnostics
cell culture media pharmaceutical formulations |
| gptkbp:bfsParent |
gptkb:HSA_(gene)
|
| gptkbp:bfsLayer |
7
|