hepatitis B vaccine

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instance_of gptkb:vaccine
gptkbp:bfsLayer 3
gptkbp:bfsParent gptkb:healthcare_organization
gptkbp:availability widely available
gptkbp:average_temperature 2-8° C
gptkbp:clinical_trial extensively studied
gptkbp:contraindication severe allergic reaction to yeast
gptkbp:defense included in EPI (Expanded Program on Immunization)
gptkbp:developer developed by recombinant DNA technology
gptkbp:dosage_form 3 doses
not routinely recommended
at birth
1-2 months after first dose
6-18 months after first dose
gptkbp:first_introduced gptkb:1981
gptkbp:healthcare significantly reduced hepatitis B incidence
https://www.w3.org/2000/01/rdf-schema#label hepatitis B vaccine
gptkbp:is_effective_against over 90% in healthy individuals
gptkbp:is_vulnerable_to long-lasting immunity
subunit vaccine
ongoing research for improved formulations
high in many countries
post-marketing surveillance conducted
0, 1, 6 months
first vaccine against a viral infection
ACIP recommends vaccination for high-risk adults
CDC recommends vaccination for all infants
administered in a series of injections
available in low-income countries
collaborations with WHO and UNICEF
considered safe for pregnant women
cost-effective intervention
distributed globally through health organizations
effective in preventing chronic infection
prevention of liver cancer
public health campaigns promote vaccination
recommended for healthcare workers
reduces transmission rates
research into combination vaccines
gptkbp:manager intramuscular injection
gptkbp:name gptkb:Recombivax_HB
gptkb:Engerix-B
gptkbp:produced_by produced using yeast cells
gptkbp:regulatory_compliance approved by FDA
approved by EMA
gptkbp:side_effect fatigue
fever
mild pain at injection site
rare serious adverse events
gptkbp:suitable_for gptkb:Person
infants
adults at risk
gptkbp:targets gptkb:healthcare_organization
gptkbp:type gptkb:recombinant_vaccine