head and neck paragangliomas

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease brain tumor
gptkbp:age	adults
gptkbp:associatedWith	SDH gene mutations hereditary paraganglioma syndromes
gptkbp:canBe	familial sporadic
gptkbp:complication	malignant transformation cranial nerve dysfunction vascular involvement
gptkbp:diagnosedBy	gptkb:CT_scan MRI biopsy angiography
gptkbp:firstDescribed	early 20th century
gptkbp:gender	female predominance
gptkbp:histology	Zellballen pattern
https://www.w3.org/2000/01/rdf-schema#label	head and neck paragangliomas
gptkbp:ICD-10_code	gptkb:D35.6
gptkbp:location	head neck
gptkbp:marking	gptkb:chromogranin_A gptkb:S-100_protein synaptophysin
gptkbp:maySecrete	gptkb:catecholamines
gptkbp:originatedIn	gptkb:paraganglionic_tissue
gptkbp:prevalence	rare
gptkbp:rarelyMetastasize	true
gptkbp:riskFactor	family history SDHB mutation SDHC mutation SDHD mutation
gptkbp:subspecies	paraganglioma Neuroendocrine Tumor
gptkbp:symptom	hearing loss cranial nerve palsy pulsatile tinnitus
gptkbp:synonym	gptkb:chemodectoma glomus tumor
gptkbp:treatment	astronomer surgery radiation therapy
gptkbp:website	gptkb:carotid_body vagal body glomus jugulare glomus tympanicum jugulotympanic region
gptkbp:bfsParent	gptkb:Hereditary_paraganglioma-pheochromocytoma_syndrome gptkb:hereditary_paraganglioma-pheochromocytoma_syndrome
gptkbp:bfsLayer	8