familial combined hyperlipidemia
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
metabolic disorder |
| gptkbp:alsoKnownAs |
FCHL
|
| gptkbp:associatedWith |
premature coronary artery disease
|
| gptkbp:causedBy |
environmental factors
single gene mutation multiple genetic factors |
| gptkbp:characterizedBy |
elevated cholesterol
elevated triglycerides increased risk of cardiovascular disease |
| gptkbp:commonIn |
adolescents
adults |
| gptkbp:diagnosedBy |
family history
lipid profile |
| gptkbp:firstDescribed |
1973
|
| https://www.w3.org/2000/01/rdf-schema#label |
familial combined hyperlipidemia
|
| gptkbp:ICD-10_code |
E78.2
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:MeSH_ID |
D006949
|
| gptkbp:OMIM |
144250
|
| gptkbp:prevalence |
1-2% of the general population
|
| gptkbp:riskFactor |
myocardial infarction
stroke atherosclerosis |
| gptkbp:treatment |
gptkb:fibrates
statins diet modification |
| gptkbp:bfsParent |
gptkb:Familial_Hypercholesterolemia
|
| gptkbp:bfsLayer |
7
|