Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:anticoagulant |
| gptkbp:activatedBy |
gptkb:factor_XIIa
contact with negatively charged surfaces |
| gptkbp:alsoKnownAs |
Hageman factor
|
| gptkbp:deficiencyAssociatedWith |
no bleeding tendency
|
| gptkbp:deficiencyCauses |
prolonged activated partial thromboplastin time
|
| gptkbp:discoveredBy |
gptkb:Oscar_Ratnoff
|
| gptkbp:discoveredIn |
1955
|
| gptkbp:EC_number |
3.4.21.38
|
| gptkbp:encodedBy |
F12 gene
|
| gptkbp:foundIn |
human blood plasma
|
| gptkbp:function |
initiates the intrinsic pathway of blood coagulation
|
| gptkbp:HGNC_ID |
3537
|
| https://www.w3.org/2000/01/rdf-schema#label |
factor XII
|
| gptkbp:locatedOnChromosome |
chromosome 5q33-qter
|
| gptkbp:molecularWeight |
80 kDa
|
| gptkbp:OMIM |
610619
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:PDB |
4A60
|
| gptkbp:presentIn |
mammals
|
| gptkbp:role |
inflammation
fibrinolysis complement system activation |
| gptkbp:structure |
single-chain glycoprotein
|
| gptkbp:UniProtID |
P00748
|
| gptkbp:bfsParent |
gptkb:factor_XIIa
|
| gptkbp:bfsLayer |
8
|