Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
complement system component |
| gptkbp:associatedWith |
autoimmune diseases
immune response age-related macular degeneration |
| gptkbp:Ba_fragment_function |
regulatory role
|
| gptkbp:Bb_fragment_function |
serine protease activity
|
| gptkbp:cleavage |
gptkb:Ba
Bb |
| gptkbp:encodedBy |
CFB gene
|
| gptkbp:foundIn |
humans
mammals |
| gptkbp:function |
alternative pathway of complement activation
cleaved by factor D |
| gptkbp:gene |
gptkb:CFB
|
| https://www.w3.org/2000/01/rdf-schema#label |
factor B
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6
|
| gptkbp:molecularWeight |
93 kDa
|
| gptkbp:OMIM |
138470
|
| gptkbp:relatedTo |
complement factor D
complement C3 complement C3b complement factor H |
| gptkbp:structure |
contains serine protease domain
contains von Willebrand factor type A domain |
| gptkbp:UniProtID |
P00751
|
| gptkbp:bfsParent |
gptkb:iC3b
gptkb:MHC_class_III_molecules |
| gptkbp:bfsLayer |
7
|